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Read length versus Depth of Coverage for Viral Quasispecies Reconstruction

Recent advancements of sequencing technology have opened up unprecedented opportunities in many application areas. Virus samples can now be sequenced efficiently with very deep coverage to infer the genetic diversity of the underlying virus populations. Several sequencing platforms with different un...

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Detalles Bibliográficos
Autores principales: Zagordi, Osvaldo, Däumer, Martin, Beisel, Christian, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463535/
https://www.ncbi.nlm.nih.gov/pubmed/23056573
http://dx.doi.org/10.1371/journal.pone.0047046