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Protective Antioxidant and Antiapoptotic Effects of ZnCl(2) in Rat Pancreatic Islets Cultured in Low and High Glucose Concentrations

AIM/HYPOTHESIS: Rat pancreatic islet cell apoptosis is minimal after prolonged culture in 10 mmol/l glucose (G10), largely increased in 5 mmol/l glucose (G5) and moderately increased in 30 mmol/l glucose (G30). This glucose-dependent asymmetric V-shaped profile is preceded by parallel changes in the...

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Detalles Bibliográficos
Autores principales: Duprez, Jessica, Roma, Leticia P., Close, Anne-Françoise, Jonas, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463538/
https://www.ncbi.nlm.nih.gov/pubmed/23056475
http://dx.doi.org/10.1371/journal.pone.0046831