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Of Mice and Men: Divergence of Gene Expression Patterns in Kidney

Since the development of methods for homologous gene recombination, mouse models have played a central role in research in renal pathophysiology. However, many published and unpublished results show that mice with genetic changes mimicking human pathogenic mutations do not display the human phenotyp...

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Detalles Bibliográficos
Autores principales: Cheval, Lydie, Pierrat, Fabien, Rajerison, Rabary, Piquemal, David, Doucet, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463552/
https://www.ncbi.nlm.nih.gov/pubmed/23056504
http://dx.doi.org/10.1371/journal.pone.0046876