The JNK- and AKT/GSK3β- Signaling Pathways Converge to Regulate Puma Induction and Neuronal Apoptosis Induced by Trophic Factor Deprivation

The AKT, GSK3 and JNK family kinases have been implicated in neuronal apoptosis associated with neuronal development and several neurodegenerative conditions. However, the mechanisms by which these kinase pathways regulate apoptosis remain unclear. In this study we have investigated the role of thes...

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Detalles Bibliográficos
Autores principales: Ambacher, Kristin K., Pitzul, Kristen B., Karajgikar, Meera, Hamilton, Alison, Ferguson, Stephen S., Cregan, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463558/
https://www.ncbi.nlm.nih.gov/pubmed/23056511
http://dx.doi.org/10.1371/journal.pone.0046885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463558/
https://www.ncbi.nlm.nih.gov/pubmed/23056511
http://dx.doi.org/10.1371/journal.pone.0046885

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