Cargando…

The JNK- and AKT/GSK3β- Signaling Pathways Converge to Regulate Puma Induction and Neuronal Apoptosis Induced by Trophic Factor Deprivation

The AKT, GSK3 and JNK family kinases have been implicated in neuronal apoptosis associated with neuronal development and several neurodegenerative conditions. However, the mechanisms by which these kinase pathways regulate apoptosis remain unclear. In this study we have investigated the role of thes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ambacher, Kristin K., Pitzul, Kristen B., Karajgikar, Meera, Hamilton, Alison, Ferguson, Stephen S., Cregan, Sean P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463558/ https://www.ncbi.nlm.nih.gov/pubmed/23056511 http://dx.doi.org/10.1371/journal.pone.0046885

Ejemplares similares

Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma
por: Guadagno, J, et al.
Publicado: (2013)

Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling
por: Schubert, Florian, et al.
Publicado: (2018)

Trophic Facilitation or Limitation? Comparative Effects of Pumas and Black Bears on the Scavenger Community
por: Allen, Maximilian L., et al.
Publicado: (2014)

Trophic convergence drives morphological convergence in marine tetrapods
por: Kelley, Neil P., et al.
Publicado: (2015)

Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma
por: Yang, Hongyan, et al.
Publicado: (2017)

Gilteritinib induces PUMA‐dependent apoptotic cell death via AKT/GSK‐3β/NF‐κB pathway in colorectal cancer cells
por: Li, Liangjun, et al.
Publicado: (2019)

Puma (Puma concolor) epididymal sperm morphometry
por: Cucho, Hernán, et al.
Publicado: (2016)

Retraction Note: Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway
por: Yang, Shida, et al.
Publicado: (2022)

Response of pumas (Puma concolor) to migration of their primary prey in Patagonia
por: Gelin, Maria L., et al.
Publicado: (2017)

A case of Anthrax in two captive pumas (Puma concolor)
por: EKEBAS, Gorkem, et al.
Publicado: (2018)

Survival and Mortality of Pumas (Puma concolor) in a Fragmented, Urbanizing Landscape
por: Vickers, T. Winston, et al.
Publicado: (2015)

The Role of Scent Marking in Mate Selection by Female Pumas (Puma concolor)
por: Allen, Maximilian L., et al.
Publicado: (2015)

Diagnostic Uncertainty and the Epidemiology of Feline Foamy Virus in Pumas (Puma concolor)
por: Dannemiller, Nicholas G., et al.
Publicado: (2020)

Dietary patterns of a versatile large carnivore, the puma (Puma concolor)
por: Karandikar, Harshad, et al.
Publicado: (2022)

A millennium of trophic stability in Atlantic cod (Gadus morhua): transition to a lower and converging trophic niche in modern times
por: Ólafsdóttir, Guðbjörg Ásta, et al.
Publicado: (2021)

Lobo vs puma
Publicado: (2004)

Puma strikes Bax
por: Letai, Anthony
Publicado: (2009)

Converging mediators from immune and trophic pathways to identify Parkinson disease dementia
por: Lue, Lih-Fen, et al.
Publicado: (2016)

Fractured Genetic Connectivity Threatens a Southern California Puma (Puma concolor) Population
por: Ernest, Holly B., et al.
Publicado: (2014)

Molecular evidence for a recent demographic expansion in the puma (Puma concolor) (Mammalia, Felidae)
por: Matte, Eunice M., et al.
Publicado: (2013)

Models of Regional Habitat Quality and Connectivity for Pumas (Puma concolor) in the Southwestern United States
por: Dickson, Brett G., et al.
Publicado: (2013)

Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth
por: Dudgeon, Crissy, et al.
Publicado: (2012)

GSK3β Is Involved in JNK2-Mediated β-Catenin Inhibition
por: Hu, Dong, et al.
Publicado: (2009)

PUMA: antiprotons and radioactive nuclei
por: Aumann, T, et al.
Publicado: (2019)

Tabaco para el puma /
por: Hernández Luna, Juan, 1962-
Publicado: (1996)

Las huellas del puma /
por: Jara, Cronwell
Publicado: (1990)

PUMA: antiprotons and radioactive nuclei
por: Obertelli, Alexandre
Publicado: (2018)

Spinal Paralysis in the Hyena and Puma
por: Todd, Charles A.
Publicado: (1881)

Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer
por: Knickelbein, Kyle, et al.
Publicado: (2018)

Correction: Models of Regional Habitat Quality and Connectivity for Pumas (Puma concolor) in the Southwestern United States
por: Dickson, Brett G., et al.
Publicado: (2014)

AKT/GSK3 signaling pathway and schizophrenia
por: Emamian, Effat S.
Publicado: (2012)

AKT/GSK3β Signaling in Glioblastoma
por: Majewska, Ewelina, et al.
Publicado: (2016)

Feline Immunodeficiency Virus and Puma Lentivirus in Florida panthers (Puma concolor coryi): Epidemiology and Diagnostic Issues
por: Miller, D. L., et al.
Publicado: (2006)

Cisplatin fails to induce puma mediated apoptosis in mucosal melanomas
por: Fritsche, Marie Kristin, et al.
Publicado: (2015)

Convergent, Parallel and Correlated Evolution of Trophic Morphologies in the Subfamily Schizothoracinae from the Qinghai-Tibetan Plateau
por: Qi, Delin, et al.
Publicado: (2012)

Synergistic Effect of Expressed miR-128 and Puma Protein on Targeted Induction of Tumor Cell Apoptosis
por: Khoshtinat Nikkhoi, Shahryar, et al.
Publicado: (2016)

Role of metabotropic glutamate receptor 5 signaling and homer in oxygen glucose deprivation-mediated astrocyte apoptosis
por: Paquet, Maryse, et al.
Publicado: (2013)

Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion
por: Shanware, Naval P., et al.
Publicado: (2014)

Pathogenic Feed-Forward Mechanisms in Alzheimer’s and Parkinson’s Disease Converge on GSK-3
por: Albeely, Abdalla M., et al.
Publicado: (2018)

PUMA: antiproton Unstable Matter Annihilation
por: Obertelli, Alexandre
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3e32q8ige2bgak5f4u07o48c3d