Cargando…

Roles of Spatial Parameters on the Oscillation of Nuclear NF-κB: Computer Simulations of a 3D Spherical Cell

Transcription factor NF-κB resides in the cytoplasm and translocates to the nucleus by application of extracellular stimuli. It is known that the nuclear NF-κB oscillates and different oscillation patterns lead to different gene expression. Nearly forty reports on modeling and simulation of nuclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohshima, Daisuke, Inoue, Jun-ichiro, Ichikawa, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463570/
https://www.ncbi.nlm.nih.gov/pubmed/23056526
http://dx.doi.org/10.1371/journal.pone.0046911