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Roles of Spatial Parameters on the Oscillation of Nuclear NF-κB: Computer Simulations of a 3D Spherical Cell
Transcription factor NF-κB resides in the cytoplasm and translocates to the nucleus by application of extracellular stimuli. It is known that the nuclear NF-κB oscillates and different oscillation patterns lead to different gene expression. Nearly forty reports on modeling and simulation of nuclear...
Autores principales: | Ohshima, Daisuke, Inoue, Jun-ichiro, Ichikawa, Kazuhisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463570/ https://www.ncbi.nlm.nih.gov/pubmed/23056526 http://dx.doi.org/10.1371/journal.pone.0046911 |
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