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Neurofibrillary Tangles and the Deposition of a Beta Amyloid Peptide with a Novel N-Terminal Epitope in the Brains of Wild Tsushima Leopard Cats

Beta amyloid (Aβ) deposits are seen in aged individuals in many of the mammalian species that possess the same Aβ amino acid sequence as humans. Conversely, neurofibrillary tangles (NFT), the other hallmark lesion of Alzheimer’s disease (AD), are extremely rare in these animals. We detected Aβ depos...

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Detalles Bibliográficos
Autores principales: Chambers, James K., Uchida, Kazuyuki, Harada, Tomoyuki, Tsuboi, Masaya, Sato, Masumi, Kubo, Masahito, Kawaguchi, Hiroaki, Miyoshi, Noriaki, Tsujimoto, Hajime, Nakayama, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463583/
https://www.ncbi.nlm.nih.gov/pubmed/23056312
http://dx.doi.org/10.1371/journal.pone.0046452