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Stabilization of Functional Recombinant Cannabinoid Receptor CB(2) in Detergent Micelles and Lipid Bilayers

Elucidation of the molecular mechanisms of activation of G protein-coupled receptors (GPCRs) is among the most challenging tasks for modern membrane biology. For studies by high resolution analytical methods, these integral membrane receptors have to be expressed in large quantities, solubilized fro...

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Detalles Bibliográficos
Autores principales: Vukoti, Krishna, Kimura, Tomohiro, Macke, Laura, Gawrisch, Klaus, Yeliseev, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463599/
https://www.ncbi.nlm.nih.gov/pubmed/23056277
http://dx.doi.org/10.1371/journal.pone.0046290