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Stabilization of Functional Recombinant Cannabinoid Receptor CB(2) in Detergent Micelles and Lipid Bilayers
Elucidation of the molecular mechanisms of activation of G protein-coupled receptors (GPCRs) is among the most challenging tasks for modern membrane biology. For studies by high resolution analytical methods, these integral membrane receptors have to be expressed in large quantities, solubilized fro...
Autores principales: | Vukoti, Krishna, Kimura, Tomohiro, Macke, Laura, Gawrisch, Klaus, Yeliseev, Alexei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463599/ https://www.ncbi.nlm.nih.gov/pubmed/23056277 http://dx.doi.org/10.1371/journal.pone.0046290 |
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