Inhibition of Notch Signaling by a γ-Secretase Inhibitor Attenuates Hepatic Fibrosis in Rats

Notch signaling is essential to the regulation of cell differentiation, and aberrant activation of this pathway is implicated in human fibrotic diseases, such as pulmonary, renal, and peritoneal fibrosis. However, the role of Notch signaling in hepatic fibrosis has not been fully investigated. In th...

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Detalles Bibliográficos
Autores principales: Chen, Yixiong, Zheng, Shaoping, Qi, Dan, Zheng, Shaojiang, Guo, Junli, Zhang, Shuling, Weng, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463607/
https://www.ncbi.nlm.nih.gov/pubmed/23056328
http://dx.doi.org/10.1371/journal.pone.0046512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463607/
https://www.ncbi.nlm.nih.gov/pubmed/23056328
http://dx.doi.org/10.1371/journal.pone.0046512

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