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Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina

In zebrafish, retinal injury stimulates Müller glia (MG) reprograming; allowing them to generate multipotent progenitors that regenerate damaged cells and restore vision. Recent studies suggest transcriptional repression may underlie these events. To identify these repressors, we compared the transc...

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Detalles Bibliográficos
Autores principales: Ramachandran, Rajesh, Zhao, Xiao-Feng, Goldman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463712/
https://www.ncbi.nlm.nih.gov/pubmed/23000964
http://dx.doi.org/10.1038/ncb2586