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Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina
In zebrafish, retinal injury stimulates Müller glia (MG) reprograming; allowing them to generate multipotent progenitors that regenerate damaged cells and restore vision. Recent studies suggest transcriptional repression may underlie these events. To identify these repressors, we compared the transc...
Autores principales: | Ramachandran, Rajesh, Zhao, Xiao-Feng, Goldman, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463712/ https://www.ncbi.nlm.nih.gov/pubmed/23000964 http://dx.doi.org/10.1038/ncb2586 |
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