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Next-generation sequencing of experimental mouse strains

Since the turn of the century the complete genome sequence of just one mouse strain, C57BL/6J, has been available. Knowing the sequence of this strain has enabled large-scale forward genetic screens to be performed, the creation of an almost complete set of embryonic stem (ES) cell lines with target...

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Detalles Bibliográficos
Autores principales: Yalcin, Binnaz, Adams, David J., Flint, Jonathan, Keane, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463794/
https://www.ncbi.nlm.nih.gov/pubmed/22772437
http://dx.doi.org/10.1007/s00335-012-9402-6