Autophagy and misfolded proteins in neurodegeneration

The accumulation of misfolded proteins in insoluble aggregates within the neuronal cytoplasm is one of the common pathological hallmarks of most adult-onset human neurodegenerative diseases. The clearance of these misfolded proteins may represent a promising therapeutic strategy in these diseases. T...

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Detalles Bibliográficos
Autores principales: Metcalf, Daniel J., García-Arencibia, Moisés, Hochfeld, Warren E., Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463804/
https://www.ncbi.nlm.nih.gov/pubmed/21095248
http://dx.doi.org/10.1016/j.expneurol.2010.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463804/
https://www.ncbi.nlm.nih.gov/pubmed/21095248
http://dx.doi.org/10.1016/j.expneurol.2010.11.003

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