Cargando…
Autophagy and misfolded proteins in neurodegeneration
The accumulation of misfolded proteins in insoluble aggregates within the neuronal cytoplasm is one of the common pathological hallmarks of most adult-onset human neurodegenerative diseases. The clearance of these misfolded proteins may represent a promising therapeutic strategy in these diseases. T...
Autores principales: | Metcalf, Daniel J., García-Arencibia, Moisés, Hochfeld, Warren E., Rubinsztein, David C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463804/ https://www.ncbi.nlm.nih.gov/pubmed/21095248 http://dx.doi.org/10.1016/j.expneurol.2010.11.003 |
Ejemplares similares
-
Autophagy, a guardian against neurodegeneration
por: García-Arencibia, Moisés, et al.
Publicado: (2010) -
Autophagy in neurodegeneration and development
por: Winslow, Ashley R., et al.
Publicado: (2008) -
Therapeutic induction of autophagy to modulate neurodegenerative disease progression
por: Hochfeld, Warren E, et al.
Publicado: (2013) -
Protein misfolding disorders and macroautophagy
por: Menzies, Fiona M, et al.
Publicado: (2011) -
Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration
por: Abramov, Andrey Y., et al.
Publicado: (2020)