Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells

The organic cation transporters OCT1, 2, and 3 (SLC22A1-3) have been implicated in the elimination of biogenic amines such as histamine. Among them, OCT3 was identified as an uptake-2 transporter, responsible for clearance of histamine. Because increasing evidence suggests the involvement of histami...

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Detalles Bibliográficos
Autores principales: Zhu, Pengxiang, Hata, Ryuji, Ogasawara, Masahito, Cao, Fang, Kameda, Kenji, Yamauchi, Kohei, Schinkel, Alfred H, Maeyama, Kazutaka, Sakanaka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463881/
https://www.ncbi.nlm.nih.gov/pubmed/22739622
http://dx.doi.org/10.1038/jcbfm.2012.92

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463881/
https://www.ncbi.nlm.nih.gov/pubmed/22739622
http://dx.doi.org/10.1038/jcbfm.2012.92

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