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Embryos generated from oocytes lacking complex N- and O-glycans have compromised development and implantation
Female mice generating oocytes lacking complex N- and O-glycans (double mutants (DM)) produce only one small litter before undergoing premature ovarian failure (POF) by 3 months. Here we investigate the basis of the small litter by evaluating ovulation rate and embryo development in DM (Mgat1(F/F)C1...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioScientifica
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464042/ https://www.ncbi.nlm.nih.gov/pubmed/22919046 http://dx.doi.org/10.1530/REP-12-0084 |