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Embryos generated from oocytes lacking complex N- and O-glycans have compromised development and implantation

Female mice generating oocytes lacking complex N- and O-glycans (double mutants (DM)) produce only one small litter before undergoing premature ovarian failure (POF) by 3 months. Here we investigate the basis of the small litter by evaluating ovulation rate and embryo development in DM (Mgat1(F/F)C1...

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Detalles Bibliográficos
Autores principales:	Grasa, Patricia, Kaune, Heidy, Williams, Suzannah A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioScientifica 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464042/ https://www.ncbi.nlm.nih.gov/pubmed/22919046 http://dx.doi.org/10.1530/REP-12-0084

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