Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles

Nonspecific association of serum molecules with short-interfering RNA (siRNA) nanoparticles can change their physiochemical characteristics, and results in reduced cellular uptake in the target tissue during the systemic siRNA delivery process. Serum albumin is the most abundant protein in the body...

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Detalles Bibliográficos
Autores principales: Kummitha, China M, Malamas, Anthony S, Lu, Zheng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464083/
https://www.ncbi.nlm.nih.gov/pubmed/23055731
http://dx.doi.org/10.2147/IJN.S34288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464083/
https://www.ncbi.nlm.nih.gov/pubmed/23055731
http://dx.doi.org/10.2147/IJN.S34288

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