Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1

BACKGROUND: The mechanism by which HIV-1 induces AIDS is still unknown. Previously, synthetic peptides corresponding to the conserved immunosuppressive (isu) domain in gp41 of HIV-1 had been shown to inhibit proliferation and to modulate cytokine expression of immune cells. The question is, whether...

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Detalles Bibliográficos
Autores principales: Morozov, Vladimir A, Morozov, Alexey V, Semaan, Marwan, Denner, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464125/
https://www.ncbi.nlm.nih.gov/pubmed/22889273
http://dx.doi.org/10.1186/1742-4690-9-67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464125/
https://www.ncbi.nlm.nih.gov/pubmed/22889273
http://dx.doi.org/10.1186/1742-4690-9-67

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