Cargando…
Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1
BACKGROUND: The mechanism by which HIV-1 induces AIDS is still unknown. Previously, synthetic peptides corresponding to the conserved immunosuppressive (isu) domain in gp41 of HIV-1 had been shown to inhibit proliferation and to modulate cytokine expression of immune cells. The question is, whether...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464125/ https://www.ncbi.nlm.nih.gov/pubmed/22889273 http://dx.doi.org/10.1186/1742-4690-9-67 |