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Avian influenza virus H5N1 induces rapid interferon-beta production but shows more potent inhibition to retinoic acid-inducible gene I expression than H1N1 in vitro

BACKGROUND: The mechanisms through which the avian influenza virus H5N1 modulate the host’s innate immune defense during invasion, remains incompletely understood. RIG-I as a pattern recognition receptor plays an important role in mediating innate immune response induced by influenza virus. So, modu...

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Detalles Bibliográficos
Autores principales: Mi, Zhiqiang, Ma, Yonghong, Tong, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464129/
https://www.ncbi.nlm.nih.gov/pubmed/22862800
http://dx.doi.org/10.1186/1743-422X-9-145