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Molecular Mechanism for the Dual Alcohol Modulation of Cys-loop Receptors
Cys-loop receptors constitute a superfamily of pentameric ligand-gated ion channels (pLGICs), including receptors for acetylcholine, serotonin, glycine and γ-aminobutyric acid. Several bacterial homologues have been identified that are excellent models for understanding allosteric binding of alcohol...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464191/ https://www.ncbi.nlm.nih.gov/pubmed/23055913 http://dx.doi.org/10.1371/journal.pcbi.1002710 |