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Rhinovirus Attenuates Non-typeable Hemophilus influenzae-stimulated IL-8 Responses via TLR2-dependent Degradation of IRAK-1

Bacterial infections following rhinovirus (RV), a common cold virus, are well documented, but pathogenic mechanisms are poorly understood. We developed animal and cell culture models to examine the effects of RV on subsequent infection with non-typeable Hemophilus influenzae (NTHi). We focused on NT...

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Detalles Bibliográficos
Autores principales: Unger, Benjamin L., Faris, Andrea N., Ganesan, Shyamala, Comstock, Adam T., Hershenson, Marc B., Sajjan, Umadevi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464227/
https://www.ncbi.nlm.nih.gov/pubmed/23055935
http://dx.doi.org/10.1371/journal.ppat.1002969