Binding of Glycoprotein Srr1 of Streptococcus agalactiae to Fibrinogen Promotes Attachment to Brain Endothelium and the Development of Meningitis

The serine-rich repeat glycoprotein Srr1 of Streptococcus agalactiae (GBS) is thought to be an important adhesin for the pathogenesis of meningitis. Although expression of Srr1 is associated with increased binding to human brain microvascular endothelial cells (hBMEC), the molecular basis for this i...

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Detalles Bibliográficos
Autores principales: Seo, Ho Seong, Mu, Rong, Kim, Brandon J., Doran, Kelly S., Sullam, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464228/
https://www.ncbi.nlm.nih.gov/pubmed/23055927
http://dx.doi.org/10.1371/journal.ppat.1002947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464228/
https://www.ncbi.nlm.nih.gov/pubmed/23055927
http://dx.doi.org/10.1371/journal.ppat.1002947

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