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Selection and Application of ssDNA Aptamers to Detect Active TB from Sputum Samples

BACKGROUND: Despite the enormous global burden of tuberculosis (TB), conventional approaches to diagnosis continue to rely on tests that have major drawbacks. The improvement of TB diagnostics relies, not only on good biomarkers, but also upon accurate detection methodologies. The 10-kDa culture fil...

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Detalles Bibliográficos
Autores principales: Rotherham, Lia S., Maserumule, Charlotte, Dheda, Keertan, Theron, Jacques, Khati, Makobetsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464247/
https://www.ncbi.nlm.nih.gov/pubmed/23056492
http://dx.doi.org/10.1371/journal.pone.0046862