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SIRT1 Regulates Dendritic Development in Hippocampal Neurons

Dendritic arborization is required for proper neuronal connectivity. SIRT1, a NAD+ dependent histone deacetylase, has been associated to ageing and longevity, which in neurons is linked to neuronal differentiation and neuroprotection. In the present study, the role of SIRT1 in dendritic development...

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Detalles Bibliográficos
Autores principales: Codocedo, Juan F., Allard, Claudio, Godoy, Juan A., Varela-Nallar, Lorena, Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464248/
https://www.ncbi.nlm.nih.gov/pubmed/23056585
http://dx.doi.org/10.1371/journal.pone.0047073