Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen

When cells swell in hypo-osmotic solutions, chloride-selective ion channels (Cl(swell)) activate to reduce intracellular osmolality and prevent catastrophic cell rupture. Despite intensive efforts to assign a molecular identity to the mammalian Cl(swell) channel, it remains unknown. In an unbiased g...

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Detalles Bibliográficos
Autores principales: Stotz, Stephanie C., Clapham, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464265/
https://www.ncbi.nlm.nih.gov/pubmed/23056495
http://dx.doi.org/10.1371/journal.pone.0046865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464265/
https://www.ncbi.nlm.nih.gov/pubmed/23056495
http://dx.doi.org/10.1371/journal.pone.0046865

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