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Virtual Screening as a Strategy for the Identification of Xenobiotics Disrupting Corticosteroid Action

BACKGROUND: Impaired corticosteroid action caused by genetic and environmental influence, including exposure to hazardous xenobiotics, contributes to the development and progression of metabolic diseases, cardiovascular complications and immune disorders. Novel strategies are thus needed for identif...

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Detalles Bibliográficos
Autores principales: Nashev, Lyubomir G., Vuorinen, Anna, Praxmarer, Lukas, Chantong, Boonrat, Cereghetti, Diego, Winiger, Rahel, Schuster, Daniela, Odermatt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464284/
https://www.ncbi.nlm.nih.gov/pubmed/23056542
http://dx.doi.org/10.1371/journal.pone.0046958