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Identification of genes underlying different methylation profiles in refractory anemia with excess blast and refractory cytopenia with multilineage dysplasia in myelodysplastic syndrome

BACKGROUND: Myelodysplastic syndrome (MDS) is a preleukemic condition that transforms into acute myeloid leukemia. However, the genetic events underlying this transformation remain poorly understood. Aberrant DNA methylation may play a causative role in the disease and its prognosis. Thus, we compar...

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Detalles Bibliográficos
Autores principales: Lee, Suee, Kwon, Hyuk-Chan, Kim, Sung-Hyun, Oh, Sung Yong, Lee, Ji Hyun, Lee, Yeon-Su, Seo, Daekwan, Han, Jin-Yeong, Kim, Hyo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464335/
https://www.ncbi.nlm.nih.gov/pubmed/23071473
http://dx.doi.org/10.5045/kjh.2012.47.3.186