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Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes

BACKGROUND: To understand the roles they play in complex diseases, genes need to be investigated in the networks they are involved in. Integration of gene expression and network data is a promising approach to prioritize disease-associated genes. Some methods have been developed in this field, but t...

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Detalles Bibliográficos
Autores principales: Wu, Chao, Zhu, Jun, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464615/
https://www.ncbi.nlm.nih.gov/pubmed/22838965
http://dx.doi.org/10.1186/1471-2105-13-182