Cargando…

Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach

Induced pluripotent stem cells (iPSCs) with potential for therapeutic applications can be derived from somatic cells via ectopic expression of a set of limited and defined transcription factors. However, due to risks of random integration of the reprogramming transgenes into the host genome, the low...

Descripción completa

Detalles Bibliográficos
Autores principales: Moschidou, Dafni, Mukherjee, Sayandip, Blundell, Michael P, Drews, Katharina, Jones, Gemma N, Abdulrazzak, Hassan, Nowakowska, Beata, Phoolchund, Anju, Lay, Kenneth, Ramasamy, T Selvee, Cananzi, Mara, Nettersheim, Daniel, Sullivan, Mark, Frost, Jennifer, Moore, Gudrun, Vermeesch, Joris R, Fisk, Nicholas M, Thrasher, Adrian J, Atala, Anthony, Adjaye, James, Schorle, Hubert, De Coppi, Paolo, Guillot, Pascale V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464631/
https://www.ncbi.nlm.nih.gov/pubmed/22760542
http://dx.doi.org/10.1038/mt.2012.117