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Valproic Acid Confers Functional Pluripotency to Human Amniotic Fluid Stem Cells in a Transgene-free Approach
Induced pluripotent stem cells (iPSCs) with potential for therapeutic applications can be derived from somatic cells via ectopic expression of a set of limited and defined transcription factors. However, due to risks of random integration of the reprogramming transgenes into the host genome, the low...
Autores principales: | Moschidou, Dafni, Mukherjee, Sayandip, Blundell, Michael P, Drews, Katharina, Jones, Gemma N, Abdulrazzak, Hassan, Nowakowska, Beata, Phoolchund, Anju, Lay, Kenneth, Ramasamy, T Selvee, Cananzi, Mara, Nettersheim, Daniel, Sullivan, Mark, Frost, Jennifer, Moore, Gudrun, Vermeesch, Joris R, Fisk, Nicholas M, Thrasher, Adrian J, Atala, Anthony, Adjaye, James, Schorle, Hubert, De Coppi, Paolo, Guillot, Pascale V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464631/ https://www.ncbi.nlm.nih.gov/pubmed/22760542 http://dx.doi.org/10.1038/mt.2012.117 |
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