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Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

Protein-tyrosine phosphatases (PTPs) are important regulators of cellular signaling and changes in PTP activity can contribute to cell transformation. Little is known about the role of PTPs in Acute Myeloid Leukemia (AML). The aim of this study was therefore to establish a PTP expression profile in...

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Detalles Bibliográficos
Autores principales: Arora, Deepika, Köthe, Susanne, van den Eijnden, Monique, van Huijsduijnen, Rob Hooft, Heidel, Florian, Fischer, Thomas, Scholl, Sebastian, Tölle, Benjamin, Böhmer, Sylvia-Annette, Lennartsson, Johan, Isken, Fabienne, Müller-Tidow, Carsten, Böhmer, Frank-D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464674/
https://www.ncbi.nlm.nih.gov/pubmed/22784513
http://dx.doi.org/10.1186/1478-811X-10-19