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Neoadjuvant bevacizumab persistently inactivates VEGF at the time of surgery despite preoperative cessation
BACKGROUND: When anti-VEGF (vascular endothelial growth factor) antibody bevacizumab is applied in neoadjuvant treatment of colorectal cancer patients with liver metastasis, 5–6 weeks between last bevacizumab dose and liver resection are currently recommended to avoid complications in wound and live...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464762/ https://www.ncbi.nlm.nih.gov/pubmed/22850548 http://dx.doi.org/10.1038/bjc.2012.342 |