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NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

In effector T and B cells immune receptor signals induce within minutes a rise of intracellular Ca(++), the activation of the phosphatase calcineurin and the translocation of NFAT transcription factors from cytosol to nucleus. In addition to this first wave of NFAT activation, in a second step the o...

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Detalles Bibliográficos
Autores principales: Serfling, Edgar, Avots, Andris, Klein-Hessling, Stefan, Rudolf, Ronald, Vaeth, Martin, Berberich-Siebelt, Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464794/
https://www.ncbi.nlm.nih.gov/pubmed/22764736
http://dx.doi.org/10.1186/1478-811X-10-16