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CXCR4 Expression Predicts Early Liver Recurrence and Poor Survival After Resection of Pancreatic Adenocarcinoma

OBJECTIVES: Liver metastasis develops in 60% of patients after resection of pancreatic adenocarcinoma (PAC) and carries a dismal prognosis, but factors predictive of liver recurrence are poorly understood. Experimental evidence suggests that liver metastasis of PAC is mediated by CXCL12/CXCR4 signal...

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Detalles Bibliográficos
Autores principales: Liao, Wei-Chih, Wang, Hsiu-Po, Huang, Hsin-Yi, Wu, Ming-Shiang, Chiang, Hung, Tien, Yu-Wen, Lin, Yu-Lin, Lin, Jaw-Town
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464805/
https://www.ncbi.nlm.nih.gov/pubmed/23238349
http://dx.doi.org/10.1038/ctg.2012.18