Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades

BACKGROUND: The membrane-bound mucins are thought to play an important biological role in cell–cell and cell–matrix interactions, in cell signaling and in modulating biological properties of cancer cell. MUC4, a transmembrane mucin is overexpressed in pancreatic tumors, while remaining undetectable...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunigal, Sateesh, Ponnusamy, Moorthy P, Momi, Navneet, Batra, Surinder K, Chellappan, Srikumar P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464875/
https://www.ncbi.nlm.nih.gov/pubmed/22537161
http://dx.doi.org/10.1186/1476-4598-11-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464875/
https://www.ncbi.nlm.nih.gov/pubmed/22537161
http://dx.doi.org/10.1186/1476-4598-11-24

Ejemplares similares