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NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death

BACKGROUND: Numerous studies have demonstrated that autophagy plays a vital role in maintaining cellular homeostasis. Interestingly, several anticancer agents were found to exert their anticancer effects by triggering autophagy. Emerging data suggest that autophagy represents a novel mechanism that...

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Detalles Bibliográficos
Autores principales: Lim, Chuan Bian, Fu, Pan You, Ky, Nung, Zhu, Hong Shuang, Feng, XiaoLing, Li, Jinming, Srinivasan, Kandhadayar Gopalan, Hamza, Mohamed Sabry, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464891/
https://www.ncbi.nlm.nih.gov/pubmed/22784363
http://dx.doi.org/10.1186/1472-6882-12-93