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Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia

Tuberous sclerosis (TS) is a common autosomal-dominant disorder characterized by tumors of the skin, lung, brain, and kidneys. Monotherapy with rapamycin however resulted in partial regression of tumors, implying the involvement of additional pathways. We have previously implicated platelet-derived...

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Detalles Bibliográficos
Autores principales: Govindarajan, Baskaran, Willoughby, Laura, Band, Hamid, Curatolo, Adam S, Veledar, Emir, Chen, Suephy, Bonner, Michael Y, Abel, Martin-Garrido, Moses, Marsha A, Arbiser, Jack L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464934/
https://www.ncbi.nlm.nih.gov/pubmed/22765013
http://dx.doi.org/10.1186/2045-824X-4-11