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Study on sustained-release metformin hydrochloride from matrix tablet: Influence of hydrophilic polymers and in vitro evaluation

The overall objective of the present work was to develop an oral sustained-release (SR) metformin tablet prepared by the direct compression method, using hydrophilic hydroxylpropylmethylcellulose (HPMC) and Guar gum polymer alone and in combination at different concentrations. Metformin hydrochlorid...

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Detalles Bibliográficos
Autores principales: Wadher, Kamlesh J, Kakde, Rajendra B, Umekar, Milind J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465141/
https://www.ncbi.nlm.nih.gov/pubmed/23071938
http://dx.doi.org/10.4103/2230-973X.85966