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Development of lyophilization cycle and effect of excipients on the stability of catalase during lyophilization

INTRODUCTION: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also includes optimization of lyophilization cycle for catalase formulations, which is...

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Detalles Bibliográficos
Autores principales: Lale, Shantanu V, Goyal, Monu, Bansal, Arvind K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465145/
https://www.ncbi.nlm.nih.gov/pubmed/23071946
http://dx.doi.org/10.4103/2230-973X.93007