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Statistical optimization of floating pulsatile drug delivery system for chronotherapy of hypertension
INTRODUCTION: A pulsatile drug delivery system is characterized by a lag time that is an interval of no drug release followed by rapid drug release. The purpose of this work was to develop hollow calcium alginate beads for floating pulsatile release of valsartan intended for chronopharmacotherapy. F...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465146/ https://www.ncbi.nlm.nih.gov/pubmed/23071945 http://dx.doi.org/10.4103/2230-973X.93005 |