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Dissolution enhancement of glimepiride using modified gum karaya as a carrier

OBJECTIVE: The aim of present investigation is to enhance in vitro dissolution of poorly soluble drug glimepiride by preparing solid dispersions using modified gum karaya. MATERIALS AND METHODS: Solid dispersions of drug were prepared by solvent evaporation method using modified gum karaya as carrie...

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Detalles Bibliográficos
Autores principales: Nagpal, Manju, Rajera, Rampal, Nagpal, Kalpana, Rakha, Pankaj, Singh, SK, Mishra, DN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465152/
https://www.ncbi.nlm.nih.gov/pubmed/23071959
http://dx.doi.org/10.4103/2230-973X.96925