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Formulation and optimization of mucoadhesive bilayer buccal tablets of atenolol using simplex design method

INTRODUCTION: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequency. Hence, the aim of this work was to design oral controlled release mucoadhesi...

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Detalles Bibliográficos
Autores principales: Shirsand, SB, Suresh, Sarasija, Keshavshetti, GG, Swamy, PV, Reddy, P Vijay Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465156/
https://www.ncbi.nlm.nih.gov/pubmed/23071958
http://dx.doi.org/10.4103/2230-973X.96924