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Formulation and optimization of mucoadhesive bilayer buccal tablets of atenolol using simplex design method
INTRODUCTION: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequency. Hence, the aim of this work was to design oral controlled release mucoadhesi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465156/ https://www.ncbi.nlm.nih.gov/pubmed/23071958 http://dx.doi.org/10.4103/2230-973X.96924 |