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Design, evaluation and in vitro - in vivo correlation of glibenclamide buccoadhesive films

BACKGROUND: Glibenclamide (G) is a popular anti-diabetic drug, belonging to the class of sulfonylurea. The drug is widely used for treating type II diabetes but it undergoes first-pass effect. A novel aspiration in treatment of diabetes, to provide greater therapeutic effect, bypass first pass effec...

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Detalles Bibliográficos
Autores principales: Prasanna, R Indira, Sankari, K Uma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465157/
https://www.ncbi.nlm.nih.gov/pubmed/23071957
http://dx.doi.org/10.4103/2230-973X.96923