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Design, evaluation and in vitro - in vivo correlation of glibenclamide buccoadhesive films
BACKGROUND: Glibenclamide (G) is a popular anti-diabetic drug, belonging to the class of sulfonylurea. The drug is widely used for treating type II diabetes but it undergoes first-pass effect. A novel aspiration in treatment of diabetes, to provide greater therapeutic effect, bypass first pass effec...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465157/ https://www.ncbi.nlm.nih.gov/pubmed/23071957 http://dx.doi.org/10.4103/2230-973X.96923 |