Effect of positional dependence and alignment strategy on modeling transcription factor binding sites

BACKGROUND: Many consensus-based and Position Weight Matrix-based methods for recognizing transcription factor binding sites (TFBS) are not well suited to the variability in the lengths of binding sites. Besides, many methods discard known binding sites while building the model. Moreover, the impact...

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Detalles Bibliográficos
Autores principales: Quader, Saad, Huang, Chun-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465234/
https://www.ncbi.nlm.nih.gov/pubmed/22748199
http://dx.doi.org/10.1186/1756-0500-5-340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465234/
https://www.ncbi.nlm.nih.gov/pubmed/22748199
http://dx.doi.org/10.1186/1756-0500-5-340

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