Inhibition of Xanthine Oxidase by Allopurinol Prevents Skeletal Muscle Atrophy: Role of p38 MAPKinase and E3 Ubiquitin Ligases

Alterations in muscle play an important role in common diseases and conditions. Reactive oxygen species (ROS) are generated during hindlimb unloading due, at least in part, to the activation of xanthine oxidase (XO). The major aim of this study was to determine the mechanism by which XO activation c...

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Detalles Bibliográficos
Autores principales: Derbre, Frederic, Ferrando, Beatriz, Gomez-Cabrera, Mari Carmen, Sanchis-Gomar, Fabian, Martinez-Bello, Vladimir E., Olaso-Gonzalez, Gloria, Diaz, Ana, Gratas-Delamarche, Arlette, Cerda, Miguel, Viña, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465256/
https://www.ncbi.nlm.nih.gov/pubmed/23071610
http://dx.doi.org/10.1371/journal.pone.0046668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465256/
https://www.ncbi.nlm.nih.gov/pubmed/23071610
http://dx.doi.org/10.1371/journal.pone.0046668

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